Antimicrobial Properties of Various Non-Antibiotic Drugs against Microorganisms

Antibiotics and antimicrobial chemotherapeutics exist in large numbers in today’s pharmaceutical market. Despite their use is becoming increasingly restricted. The reason behind such a rapid decline is largely attributed to the development of drug resistance among microorganisms. Such a phenomenon is coupled by the toxicity possessed by many antimicrobials. Multiple drug resistance among highly infective microorganisms generates a major obstacle to clinical applications in recent years. As development of a new broad range antimicrobial agent is difficult and takes several years, increasing the activity of existing antibiotics would be a future solution to this challenge. However, there is a search for newer antimicrobial agents that can overcome these drawbacks. Studies in this line have exposed the fact that several compounds, belonging to various pharmacological classes, possess moderate to powerful antibacterial activity.